Inhibitors of SP140 and their use in therapy

Invention Grant

US09018184B2 Inhibitors of SP140 and their use in therapy 有权

Title translation: SP140的抑制剂及其在治疗中的应用

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Patent Title: Inhibitors of SP140 and their use in therapy
Patent Title (中): SP140的抑制剂及其在治疗中的应用
Application No.: US13883091

Application Date: 2011-11-23
Publication No.: US09018184B2

Publication Date: 2015-04-28
Inventor: Kevin Lee , David Francis Tough
Applicant: Kevin Lee , David Francis Tough
Applicant Address: GB Brentford, Middlesex
Assignee: Glaxo Group Limited
Current Assignee: Glaxo Group Limited
Current Assignee Address: GB Brentford, Middlesex
Agent Robert H. Brink
Priority: GB1020015.2 20101125
International Application: PCT/EP2011/070781 WO 20111123
International Announcement: WO2012/069525 WO 20120531
Main IPC: C12N15/11
IPC: C12N15/11 ; C12Q1/68 ; A61K31/713 ; C12N15/113

Inhibitors of SP140 and their use in therapy

Abstract:

A method of treating autoimmune and inflammatory diseases or conditions in a mammal, such as a human, which comprises the administration of a inhibitor of bromodomain-containing protein: SP140.

Abstract(Chinese):

治疗哺乳动物（例如人）中的自身免疫性和炎性疾病或病症的方法，其包括施用含有溴结构域的蛋白质的抑制剂：SP140。

Public/Granted literature

US20130225661A1 Inhibitors Of SP140 And Their Use In Therapy Public/Granted day:2013-08-29

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Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术
C12N15/11	..DNA或RNA片段；其修饰形成（不用于重组技术的DNA或RNA入C07H21/00）