Invention Grant
US09018255B2 Esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them, and their use as inhibitors of the thioredoxin—thioredoxin reductase system
有权
（酰氧基甲基）丙烯酰胺的酯，含有它们的药物组合物及其作为硫氧还蛋白硫氧还蛋白还原酶系统的抑制剂的用途
- Patent Title: Esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them, and their use as inhibitors of the thioredoxin—thioredoxin reductase system
- Patent Title (中): （酰氧基甲基）丙烯酰胺的酯，含有它们的药物组合物及其作为硫氧还蛋白硫氧还蛋白还原酶系统的抑制剂的用途
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Application No.: US13879609Application Date: 2011-10-16
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Publication No.: US09018255B2Publication Date: 2015-04-28
- Inventor: Ryszard Ostaszewski , Szymon Klossowski , Izabela Ziuzia , Angelika Szokalska , Marta Swiech , Jakub Golab
- Applicant: Ryszard Ostaszewski , Szymon Klossowski , Izabela Ziuzia , Angelika Szokalska , Marta Swiech , Jakub Golab
- Applicant Address: PL PL
- Assignee: Instytut Chemii Organicznej Polskiej Akademii Nauk,Warszawski Uniwersytet Medyczny
- Current Assignee: Instytut Chemii Organicznej Polskiej Akademii Nauk,Warszawski Uniwersytet Medyczny
- Current Assignee Address: PL PL
- Agency: Fox Rothschild LLP
- Agent Shahnam Sharareh
- Priority: PL392651 20101016
- International Application: PCT/PL2011/050041 WO 20111016
- International Announcement: WO2012/050465 WO 20120419
- Main IPC: A01N37/10
- IPC: A01N37/10 ; A61K31/235 ; C07C229/00 ; C07C235/28
Abstract:
The subject of the present invention are novel esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them and their use in the production of drugs for the prophylaxis or treatment of oncogenic diseases and diseases connected with increased cell proliferation.
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