发明授权
US09023384B2 Liposome and method for injecting substance to cell using this liposome
有权
脂质体和使用该脂质体向细胞注射物质的方法
- 专利标题： Liposome and method for injecting substance to cell using this liposome
- 专利标题（中）： 脂质体和使用该脂质体向细胞注射物质的方法
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申请号： US11666736申请日： 2005-11-02
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公开(公告)号： US09023384B2公开(公告)日： 2015-05-05
- 发明人: Ikuo Morita , Kazunari Akiyoshi , Shinichiro Nomura
- 申请人： Ikuo Morita , Kazunari Akiyoshi , Shinichiro Nomura
- 申请人地址： JP Tokyo JP Tokyo
- 专利权人： Tokyo Medical and Dental University,Dai Nippon Printing Co., Ltd.
- 当前专利权人： Tokyo Medical and Dental University,Dai Nippon Printing Co., Ltd.
- 当前专利权人地址： JP Tokyo JP Tokyo
- 代理机构： Sughrue Mion, PLLC
- 优先权： JP2004-319685 20041102
- 国际申请： PCT/JP2005/020486 WO 20051102
- 国际公布： WO2006/049307 WO 20060511
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K47/42 ; C12N5/00 ; A61K38/17
摘要：
It is intended to efficiently inject into a target cell, a substance charged within a liposome. The present inventors have found that connexin synthesized within a liposome is introduced as connexon having a gap junction function into the liposome membrane. Specifically, the liposome according to the present invention is a liposome in which connexon composed of connexin synthesized by an in-vitro protein synthesis system is incorporated in a state of having a gap junction function.