发明授权
US09023858B2 Substituted pyrido[2,3-d]pyrimidines as delta-5-desaturase inhibitors
有权
取代的吡啶并[2,3-d]嘧啶作为δ-5-去饱和酶抑制剂
- 专利标题: Substituted pyrido[2,3-d]pyrimidines as delta-5-desaturase inhibitors
- 专利标题(中): 取代的吡啶并[2,3-d]嘧啶作为δ-5-去饱和酶抑制剂
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申请号: US13811755申请日: 2011-07-22
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公开(公告)号: US09023858B2公开(公告)日: 2015-05-05
- 发明人: Nobuyuki Matsunaga , Hideo Suzuki , Kouhei Asano , Hidekazu Tokuhara , Takeshi Yamamoto , Rei Okamoto
- 申请人: Nobuyuki Matsunaga , Hideo Suzuki , Kouhei Asano , Hidekazu Tokuhara , Takeshi Yamamoto , Rei Okamoto
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2010-166475 20100723; JP2011-122796 20110531
- 国际申请: PCT/JP2011/066766 WO 20110722
- 国际公布: WO2012/011591 WO 20120126
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D487/04 ; C07D471/04 ; C07D475/02 ; C07D513/04
摘要:
The present invention provides a compound useful for the prophylaxis or treatment of eicosanoid-associated diseases such as atherosclerosis, atherothrombosis, diabetes, obesity, asthma, fever, pain, cancer, rheumatism, osteoarthritis, atopic dermatitis and the like, and having superior pharmacological action, physicochemical properties and the like.The present invention relates to a compound represented by the following formula: wherein each symbol is as defined in the specification, or a salt thereof.
公开/授权文献
- US20130131050A1 FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF 公开/授权日:2013-05-23
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