A method and an apparatus for playing audio of an attendant at a remote end and a remote video conference system are provided. The method includes: receiving audio of an attendant at a remote site; and by means of two or more loudspeakers mounted at a top and a bottom of a remote image presentation device at a local site, simulating an audio transmission path of the audio of the attendant at the remote site between the two or more loudspeakers and an attendant at the local site through a predetermined algorithm, where the simulating means that the audio transmission path is simulated between an image of the head of the attendant at the remote site displayed in the remote image presentation device, and the head of the attendant at the local site.