发明授权
- 专利标题: Method for manufacturing spilanthol and intermediate manufacturing product therefor
- 专利标题(中): 制备微量金属的方法及其中间制造产品
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申请号: US13383547申请日: 2010-07-14
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公开(公告)号: US09029593B2公开(公告)日: 2015-05-12
- 发明人: Shigeru Tanaka , Kenya Ishida , Kenji Yagi , Hideo Ujihara
- 申请人: Shigeru Tanaka , Kenya Ishida , Kenji Yagi , Hideo Ujihara
- 申请人地址: JP Tokyo
- 专利权人: Takasago International Corporation
- 当前专利权人: Takasago International Corporation
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2009-165530 20090714
- 国际申请: PCT/JP2010/061912 WO 20100714
- 国际公布: WO2011/007807 WO 20110120
- 主分类号: C07C231/12
- IPC分类号: C07C231/12 ; C07C235/28 ; A61K31/16 ; A61K8/42 ; A61Q13/00 ; C07C233/09 ; A23L2/56 ; A23L1/226 ; C11B9/00
摘要:
Provided is an amide ester that is useful as an intermediate manufacturing product for an aroma compound such as spilanthol or the like. Also provided is a spilanthol manufacturing method using said amide ester. High-purity spilanthol can be manufactured by reacting an amide ester represented by general formula (1) with a basic compound. (In the formula, R1 represents a C1-6 alkyl group or a phenyl group that may be substituted with a C1-4 alkyl group, a C1-4 alkoxy group, or a halogen atom; R2 represents a C1-8 hydrocarbon group; and the wavy lines represent cis configurations, trans configurations, or a mixture of the two configurations.)
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