发明授权
- 专利标题: Pyrrolopyrimidine and purine derivatives
- 专利标题(中): 吡咯并嘧啶和嘌呤衍生物
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申请号: US13617035申请日: 2012-09-14
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公开(公告)号: US09040547B2公开(公告)日: 2015-05-26
- 发明人: Hengmiao Cheng , Theodore Otto Johnson, Jr. , John Charles Kath , Kevin Kun-Chin Liu , Elizabeth Ann Lunney , Asako Nagata , Sajiv Krishnan Nair , Simon Paul Planken , Scott Channing Sutton
- 申请人: Hengmiao Cheng , Theodore Otto Johnson, Jr. , John Charles Kath , Kevin Kun-Chin Liu , Elizabeth Ann Lunney , Asako Nagata , Sajiv Krishnan Nair , Simon Paul Planken , Scott Channing Sutton
- 申请人地址: US NY New York
- 专利权人: PFIZER INC.
- 当前专利权人: PFIZER INC.
- 当前专利权人地址: US NY New York
- 代理商 Suzanne M. Bates; Stephen D. Prodnuk
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K31/5377 ; A61K31/52 ; C07D473/16 ; C07D487/04
摘要:
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
公开/授权文献
- US20130079324A1 PYRROLOPYRIMIDINE AND PURINE DERIVATIVES 公开/授权日:2013-03-28
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