The present invention relates to a wireless communication system, and more particularly, to a method and apparatus for efficient feedback in a wireless communication system that supports multiple antennas. A method for transmitting, via an uplink, channel state information for downlink transmission in a wireless communication system according to one embodiment of the present invention, comprises the following steps: receiving a downlink signal via a downlink channel; generating an RI for the downlink channel, selecting a first PMI and a second PMI on the basis of the rank indicated by the generated RI, and calculating a CQI on the basis of precoding information determined by the combination of the selected first and second PMIs; and transmitting the RI, the first PMI, the second PMI, and/or the CQI via an uplink channel, wherein said first PMI and second PMI can be transmitted on different uplink subframes if the uplink channel is a PUCCH.