The present application relates to an image registration method, comprising: selecting a registration source image {pi} and a registration target image {qj}; applying a random perturbation to {pi} in accordance with a preset random perturbation control parameter σ so that it is deformed to obtain {pi′}, and obtaining a set of closest points, i.e., {gj′}, on {qj} corresponding to points on {pi′}; performing an iterative operation on {pi′} and {qj′} in accordance with a preset initial coordinate transformation H0 to obtain a coordinate transformation {H1}, 0