There are provided methods and apparatus for transform selection in video coding. An apparatus includes a video encoder for encoding at least a block in a picture by selecting a transform to apply to a residue of the block from a set of two or more available transforms. The transform is selected based on at least one of an inter prediction mode used to predict at least one reference for the block, one or more values corresponding to a motion vector, a value of a residue of one or more previously encoded blocks, a value of prediction data for the block, one or more transform selections of one or more neighboring reconstructed blocks, and a quantization step applied to transform coefficients for the residue of the block.