Substantially homogenous compositions in accordance with the present disclosure can exist in various forms, such as bulk materials, coatings, films, laminates, inserts, or overlays, and include at least one polymer such as SU-8, at least one liquid lubricant, and optionally at least one nanomaterial that serves as an inorganic filler material. Such compositions exhibit enhanced tribological and mechanical properties compared to the at least one polymer in isolation, for instance, a 50% or greater coefficient of friction reduction, a 100% or greater wear life increase, a 10% or greater elastic modulus increase, and/or a 10% or greater hardness increase. The at least one nanomaterial can include a first nanomaterial providing increased hardness, and a second nanomaterial providing increased elastic modulus. Compositions in accordance with the present disclosure are suitable for biological and non-biological applications.