A method and apparatus is disclosed herein for motion vector prediction and coding. In one embodiment, the method comprises: deriving N motion vector predictors for a first block that has N motion vectors corresponding to N lists of reference frames and a current frame, including constructing one of the N motion vector predictors when a second block that neighbors the first block and is used for prediction has at least one invalid motion vector, where N is an integer greater than 1; generating N differential motion vectors based on the N motion vectors and N motion vector predictors; and encoding the N differential motion vectors.