发明授权
US09062043B2 Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators
有权
融合的三环化合物作为丝氨酸 - 苏氨酸蛋白激酶和PARP调节剂
- 专利标题： Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators
- 专利标题（中）： 融合的三环化合物作为丝氨酸 - 苏氨酸蛋白激酶和PARP调节剂
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申请号： US13035640申请日： 2011-02-25
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公开(公告)号： US09062043B2公开(公告)日： 2015-06-23
- 发明人: Peter C. Chua , Fabrice Pierre , Jeffrey P. Whitten
- 申请人： Peter C. Chua , Fabrice Pierre , Jeffrey P. Whitten
- 申请人地址： TW New Taipei
- 专利权人： SENHWA BIOSCIENCES, INC.
- 当前专利权人： SENHWA BIOSCIENCES, INC.
- 当前专利权人地址： TW New Taipei
- 代理机构： Cooley LLP
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D221/12 ; C07D401/04 ; C07D495/04 ; C07D513/04
摘要：
The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate casein kinase (CK) activity and/or poly(ADP-ribose)polymerase (PARP) activity. The invention also relates in part to methods for using such molecules.