发明授权
- 专利标题： Peptidic antigen that induces antibody recognizing three-dimensional structure of HIV and method for synthesizing same
- 专利标题（中）： 诱导抗体识别HIV三维结构的肽抗原及其合成方法
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申请号： US13319813申请日： 2010-05-14
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公开(公告)号： US09066983B2公开(公告)日： 2015-06-30
- 发明人: Hirokazu Tamamura , Toru Nakahara , Wataru Nomura
- 申请人： Hirokazu Tamamura , Toru Nakahara , Wataru Nomura
- 申请人地址： JP Tokyo
- 专利权人： NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
- 当前专利权人： NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
- 当前专利权人地址： JP Tokyo
- 代理机构： Hogan Lovells US LLP
- 优先权： JP2009-120352 20090518
- 国际申请： PCT/JP2010/003280 WO 20100514
- 国际公布： WO2010/134305 WO 20101125
- 主分类号： A61K39/385
- IPC分类号： A61K39/385 ; A61K39/21 ; A61K47/48 ; C07K14/005 ; C07K16/10 ; A61K39/00
摘要：
An object of the present invention is to provide an HIV antibody-inducing peptide antigen that is effective in developing an antibody or a vaccine having specificity and binding activity for the three-dimensional structure of a neutralization target, i.e. the mechanism by which HIV invades a target cell; a method for synthesizing the same; a vaccine comprising the peptide antigen, or an HIV three-dimensional structure-recognizing antibody induced by the peptide antigen; and a preventive and/or therapeutic agent for HIV infection comprising the peptide antigen, the vaccine, or the HIV three-dimensional structure-recognizing antibody as an active ingredient.