Methods and systems for authentication of a device are disclosed. An exemplary method includes transmitting an energy towards the device including a material, monitoring a response of the device to the transmitted energy, generating a signature of the device based on the response of the device to the transmitted energy, comparing the device signature to an enrolled signature for the device, and indicating that authentication of the device is successful when the generated signature matches the enrolled signature. An exemplary system includes a transmitter configured to transmit an energy towards the device, a receiver configured to monitor a response of the device, and a processor configured to generate a signature of the device based on the response of the device, compare the device signature to an enrolled signature for the device, and indicate that authentication of the device is successful when the generated signature matches the enrolled signature.