发明授权
- 专利标题： Method of predicting a predisposition to QT prolongation
- 专利标题（中）： 预测QT延长倾向的方法
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申请号： US13263075申请日： 2010-04-05
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公开(公告)号： US09074255B2公开(公告)日： 2015-07-07
- 发明人: Christian Lavedan , Simona Volpi , Louis Licamele
- 申请人： Christian Lavedan , Simona Volpi , Louis Licamele
- 申请人地址： US DC Washington
- 专利权人： Vanda Pharmaceuticals, Inc.
- 当前专利权人： Vanda Pharmaceuticals, Inc.
- 当前专利权人地址： US DC Washington
- 代理机构： Hoffman Warnick LLC
- 国际申请： PCT/US2010/029931 WO 20100405
- 国际公布： WO2010/117937 WO 20101014
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention describes an association between genetic polymorphisms in the FAM13A1 (family with sequence similarity 13, member A1) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval- prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.
公开/授权文献
- US20120058201A1 METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION 公开/授权日：2012-03-08
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