Invention Grant
US09079906B2 Triazolopyridazines as PAR1 inhibitors, production thereof, and use as medicaments
有权
三唑并嘧啶作为PAR1抑制剂，其生产和用作药物
- Patent Title: Triazolopyridazines as PAR1 inhibitors, production thereof, and use as medicaments
- Patent Title (中): 三唑并嘧啶作为PAR1抑制剂，其生产和用作药物
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Application No.: US13243118Application Date: 2011-09-23
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Publication No.: US09079906B2Publication Date: 2015-07-14
- Inventor: Uwe Heinelt , Volkmar Wehner , Matthias Herrmann , Karl Schoenafinger , Henning Steinhagen , Bodo Scheiper
- Applicant: Uwe Heinelt , Volkmar Wehner , Matthias Herrmann , Karl Schoenafinger , Henning Steinhagen , Bodo Scheiper
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Priority: EP08290112 20080205
- Main IPC: A01N43/58
- IPC: A01N43/58 ; A01N43/60 ; A61K31/50 ; A61K31/495 ; C07D487/04 ; A61K31/5025
Abstract:
The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R6, R7, R8, Q1, Q2 and Q3 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.
Public/Granted literature
- US20120010203A1 TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS Public/Granted day:2012-01-12
Information query
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