Provided is a system and method for synchronization between digital-to-analog converters (DAC) for high speed signal processing. A synchronization method of a multi-DAC apparatus may include: inputting a clock to a multiplexer (MUX) DAC; dividing the clock into a first clock and a second clock; transferring a phase difference between the first clock and the second clock to a D flip-flop; and synchronizing the first clock and the second clock by processing the phase difference.