- 专利标题: Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
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申请号: US12883369申请日: 2010-09-16
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公开(公告)号: US09089497B2公开(公告)日: 2015-07-28
- 发明人: Mark Hokenson , Keith A. Oberg
- 申请人: Mark Hokenson , Keith A. Oberg
- 申请人地址: US CA Valencia
- 专利权人: MannKind Corporation
- 当前专利权人: MannKind Corporation
- 当前专利权人地址: US CA Valencia
- 代理机构: K&L Gates LLP
- 代理商 Louis C. Cullman; Robert W. Winn
- 主分类号: A61K38/28
- IPC分类号: A61K38/28 ; A61K38/29 ; A61K9/14 ; A61K9/28 ; A61K9/50 ; A61K9/16 ; A61K38/13 ; A61K38/25 ; A61K38/27
摘要:
Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.
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