Invention Grant
- Patent Title: Fluorescent imaging with substituted cyanine dyes
- Patent Title (中): 用取代花青染料进行荧光成像
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Application No.: US13836202Application Date: 2013-03-15
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Publication No.: US09089603B2Publication Date: 2015-07-28
- Inventor: Xinshe Xu , Daniel R. Draney , Mark Cradduck , Lael Cheung , Kousik Kundu , William M. Volcheck
- Applicant: LI-COR, INC.
- Applicant Address: US NE Lincoln
- Assignee: LI-COR, INC.
- Current Assignee: LI-COR, INC.
- Current Assignee Address: US NE Lincoln
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K49/00 ; C09B23/01 ; C09B23/08 ; C09B69/00 ; G01N33/574 ; G01N33/58 ; C07F9/6561 ; C07K19/00 ; C08B37/08
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented: wherein Q is a portion of a polymethine bridge: Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
Public/Granted literature
- US20130280172A1 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES Public/Granted day:2013-10-24
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