Systems and methods for security key transmission with strong pairing to a destination client are disclosed. A security key may be generated by an on-chip key generator, an off-chip device, and/or software. A rule may then be paired with the security key and an address associated with the security key. The rule may define permissible usage by a destination module, which is defined by the associated address. The rule may comprise a command word, which may be implemented using a data structure associated with a permissible algorithm type, a security key size, and/or a security key source.