- 专利标题: Method for the production of ceftobiprole medocaril
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申请号: US13320414申请日: 2010-05-25
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公开(公告)号: US09096610B2公开(公告)日: 2015-08-04
- 发明人: Peter Kremminger , Johannes Ludescher , Hubert Sturm
- 申请人: Peter Kremminger , Johannes Ludescher , Hubert Sturm
- 申请人地址: CH Basel
- 专利权人: SANDOZ AG
- 当前专利权人: SANDOZ AG
- 当前专利权人地址: CH Basel
- 代理机构: Manelli Selter PLLC
- 代理商 Jeffrey S. Melcher
- 优先权: EP09161028 20090525
- 国际申请: PCT/EP2010/057104 WO 20100525
- 国际公布: WO2010/136422 WO 20101202
- 主分类号: C07D501/56
- IPC分类号: C07D501/56 ; C07D501/04 ; C07D501/18
摘要:
The present invention relates to a method for the production of organic compounds, in particular sodium (6R,7R)-7-[(Z)-2-(5-amino-[1,2,4]thiadiazol-3-yl)-2-hydroxyimino-acetylamino]-8-oxo-3-[(E)-(R)-1′-(5-methyl-2-oxo-[1,3]-dioxol-4-ylmethoxycarbonyl)-2-oxo-[1,3′]bipyrrolidinyl-3-ylidenemethyl]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate (ceftobiprole medocaril), and compounds of the general formula (1) and of the general formula (2), the compounds themselves and intermediates in the production according to the invention.
公开/授权文献
- US20120116070A1 METHOD FOR THE PRODUCTION OF CEFTOBIPROLE MEDOCARIL 公开/授权日:2012-05-10
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