- 专利标题: Metal abstraction peptide (MAP) tag and associated methods
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申请号: US13596281申请日: 2012-08-28
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公开(公告)号: US09096652B2公开(公告)日: 2015-08-04
- 发明人: Jennifer Ann Stowell Laurence , Anthony Andrew Vartia , Mary Elizabeth Krause
- 申请人: Jennifer Ann Stowell Laurence , Anthony Andrew Vartia , Mary Elizabeth Krause
- 申请人地址: US KS Lawrence
- 专利权人: UNIVERSITY OF KANSAS
- 当前专利权人: UNIVERSITY OF KANSAS
- 当前专利权人地址: US KS Lawrence
- 代理机构: Wilson Sonsini Goodrich & Rosati
- 主分类号: C07K4/00
- IPC分类号: C07K4/00 ; C07K2/00 ; C07K19/00 ; C07K5/00 ; C07K5/097 ; C07K16/00 ; C07K5/093 ; G01N31/22 ; G01N33/20 ; G01N21/78 ; G01N33/84 ; A61K38/00
摘要:
Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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