发明授权
- 专利标题： Peptide aptamers that bind to the rep proteins of ssDNA viruses
- 专利标题（中）： 结合ssDNA病毒rep蛋白的肽适体
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申请号： US13437688申请日： 2012-04-02
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公开(公告)号： US09102705B2公开(公告)日： 2015-08-11
- 发明人: Linda Hanley-Bowdoin , Luisa Lopez-Ochoa
- 申请人： Linda Hanley-Bowdoin , Luisa Lopez-Ochoa
- 申请人地址： US NC Raleigh
- 专利权人： North Carolina State University
- 当前专利权人： North Carolina State University
- 当前专利权人地址： US NC Raleigh
- 代理机构： Myers Bigel Sibley & Sajovec, P.A.
- 主分类号： C07K7/08
- IPC分类号： C07K7/08 ; C07K7/06 ; A61K38/04 ; C07K14/00 ; C12Q1/00 ; A61K38/00
摘要：
Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
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