Amplifiers with inductive degeneration and configurable gain and input matching are disclosed. In an exemplary design, an apparatus includes a gain transistor, an inductor, and an input matching circuit for an amplifier. The gain transistor has a variable gain determined based on its bias current. The inductor is coupled between the gain transistor and circuit ground. The input matching circuit is selectively coupled to the gain transistor based on the variable gain of the gain transistor. For example, the input matching circuit may be coupled to the gain transistor in a low-gain mode and decoupled from the gain transistor in the high-gain mode. In an exemplary design, the input matching circuit includes a resistor, a capacitor, and a second transistor coupled in series. The resistor is used for input matching of the amplifier. The second transistor couples or decouples the resistor to or from the gain transistor.