According to an aspect of an embodiment of the present disclosure, a method of relaxing a timing constraint associated with reducing inter-symbol interference (ISI) of input data includes adding an ISI cancellation value to input data received at a first clock rate to generate first speculative data. The method further includes subtracting the ISI cancellation value from the input data to generate second speculative data. The method also includes sampling the first speculative data and the second speculative data at a second clock rate that is one-fourth of the first clock rate such that a timing constraint associated with performing the ISI reduction is relaxed.