Systems and methods for managing the transmission of multiple signals on one or more uplink (UL) channels using carrier aggregation in LTE-A systems. A UE simultaneously transmits signals such as ACK/NACK and periodic CSI using one or more uplink channels, such as a physical uplink shared channel (PUSCH) and/or a physical uplink control channel (PUCCH), by increasing the resources used to transmit at least one of those signals. According to one aspect, a UE simultaneously transmits ACK/NACK signals and periodic CSI signals by multiplexing those signals on the PUSCH. Certain aspects avoid frequently dropped periodic CSI signals and provide mechanisms to ensure that ACK/NACK signals are transmitted.