发明授权
- 专利标题： Synthesis process of dasatinib and intermediate thereof
- 专利标题（中）： 达沙替尼及其中间体的合成方法
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申请号： US13576637申请日： 2011-01-30
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公开(公告)号： US09108954B2公开(公告)日： 2015-08-18
- 发明人: Rong Yan , Hao Yang , Wen Hou , Yongxiang Xu
- 申请人： Rong Yan , Hao Yang , Wen Hou , Yongxiang Xu
- 申请人地址： CN Jiangsu CN Jiangsu
- 专利权人： Nan Jing Cavendish Bio-Engineering Technology Co., Ltd.,Rong Yan
- 当前专利权人： Nan Jing Cavendish Bio-Engineering Technology Co., Ltd.,Rong Yan
- 当前专利权人地址： CN Jiangsu CN Jiangsu
- 代理机构： Sunstone IP
- 优先权： CN201010104295 20100202; CN201010169637 20100426
- 国际申请： PCT/CN2011/070828 WO 20110130
- 国际公布： WO2011/095126 WO 20110811
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; C07D417/14
摘要：
Synthesis process of dasatinib is disclosed, which includes the step of reacting the compound of formula I with that of formula II to obtain the compound of formula III. Also disclosed is the compound of formula III which is used as an intermediate for synthesizing dasatinib. The substituents of R1, R2, R3 or R4 in formulae I, II or III are defined as in the description.
公开/授权文献
- US20130030177A1 SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF 公开/授权日：2013-01-31