发明授权
- 专利标题： Process for the preparation of an orexin receptor antagonist
- 专利标题（中）： 食欲肽受体拮抗剂的制备方法
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申请号： US14002221申请日： 2012-02-27
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公开(公告)号： US09108959B2公开(公告)日： 2015-08-18
- 发明人: Carl A. Baxter , Edward Cleator , Faye Sheen , Shane W. Krska , Gavin Stewart , Neil Strotman , Debra J. Wallace , Timothy Wright
- 申请人： Carl A. Baxter , Edward Cleator , Faye Sheen , Shane W. Krska , Gavin Stewart , Neil Strotman , Debra J. Wallace , Timothy Wright
- 申请人地址： US NJ Rahway GB Hoddesdon
- 专利权人： Merck Sharp & Dohme Corp.,Merck Sharp & Dohme Limited
- 当前专利权人： Merck Sharp & Dohme Corp.,Merck Sharp & Dohme Limited
- 当前专利权人地址： US NJ Rahway GB Hoddesdon
- 代理商 J. Eric Thies; John C. Todaro
- 国际申请： PCT/US2012/026691 WO 20120227
- 国际公布： WO2012/148553 WO 20121101
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D413/04 ; C07D413/14 ; C07D249/06 ; A61K31/55
摘要：
The present invention is directed to processes for preparing a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is further directed to crystalline forms of this diazepane compound and pharmaceutical compositions thereof.
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