Invention Grant
- Patent Title: Process for the preparation of an orexin receptor antagonist
- Patent Title (中): 食欲肽受体拮抗剂的制备方法
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Application No.: US14002221Application Date: 2012-02-27
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Publication No.: US09108959B2Publication Date: 2015-08-18
- Inventor: Carl A. Baxter , Edward Cleator , Faye Sheen , Shane W. Krska , Gavin Stewart , Neil Strotman , Debra J. Wallace , Timothy Wright
- Applicant: Carl A. Baxter , Edward Cleator , Faye Sheen , Shane W. Krska , Gavin Stewart , Neil Strotman , Debra J. Wallace , Timothy Wright
- Applicant Address: US NJ Rahway GB Hoddesdon
- Assignee: Merck Sharp & Dohme Corp.,Merck Sharp & Dohme Limited
- Current Assignee: Merck Sharp & Dohme Corp.,Merck Sharp & Dohme Limited
- Current Assignee Address: US NJ Rahway GB Hoddesdon
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2012/026691 WO 20120227
- International Announcement: WO2012/148553 WO 20121101
- Main IPC: A61K31/551
- IPC: A61K31/551 ; C07D413/04 ; C07D413/14 ; C07D249/06 ; A61K31/55
Abstract:
The present invention is directed to processes for preparing a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is further directed to crystalline forms of this diazepane compound and pharmaceutical compositions thereof.
Public/Granted literature
- US20130331379A1 PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST Public/Granted day:2013-12-12
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