发明授权
US09115127B2 Benzimidazole and azabenzimidazole compounds that inhibit anaplastic lymphoma kinase
有权
抑制间变性淋巴瘤激酶的苯并咪唑和氮杂苯并咪唑化合物
- 专利标题: Benzimidazole and azabenzimidazole compounds that inhibit anaplastic lymphoma kinase
- 专利标题(中): 抑制间变性淋巴瘤激酶的苯并咪唑和氮杂苯并咪唑化合物
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申请号: US13813813申请日: 2011-07-28
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公开(公告)号: US09115127B2公开(公告)日: 2015-08-25
- 发明人: Christiane M. Boezio , Alan C. Cheng , Deborah Choquette , Richard T. Lewis , Michele H. Potashman , Karina Romero , John C. Stellwagen , Douglas A. Whittington
- 申请人: Christiane M. Boezio , Alan C. Cheng , Deborah Choquette , Richard T. Lewis , Michele H. Potashman , Karina Romero , John C. Stellwagen , Douglas A. Whittington
- 申请人地址: US CA Thousand Oaks
- 专利权人: AMGEN INC.
- 当前专利权人: AMGEN INC.
- 当前专利权人地址: US CA Thousand Oaks
- 代理机构: Choate, Hall & Stewart LLP
- 代理商 Brenda Herschbach Jarrell; Kristen C. Buteau
- 国际申请: PCT/US2011/045703 WO 20110728
- 国际公布: WO2012/018668 WO 20120209
- 主分类号: C07D235/30
- IPC分类号: C07D235/30 ; C07D235/32 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/06 ; C07D403/08 ; C07D403/14 ; C07D417/04 ; C07D413/04 ; A61P35/00 ; C07D471/04 ; C07D417/06 ; C07D487/04 ; C07D401/10 ; C07D413/10 ; C07D413/14 ; C07D417/14 ; C07D417/12 ; C07D519/00
摘要:
Compounds of Formula (I) are useful inhibitors of anaplastic lymphoma kinase. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.