Invention Grant
- Patent Title: Pyridine compounds as sodium channel blockers
- Patent Title (中): 吡啶化合物作为钠通道阻断剂
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Application No.: US13810089Application Date: 2011-07-15
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Publication No.: US09120752B2Publication Date: 2015-09-01
- Inventor: Donald J. Kyle , Chiyou Ni , Minnie Park , Laykea Tafesse
- Applicant: Donald J. Kyle , Chiyou Ni , Minnie Park , Laykea Tafesse
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma, L.P.
- Current Assignee: Purdue Pharma, L.P.
- Current Assignee Address: US CT Stamford
- Agency: Purdue Pharma, L.P.
- Agent Alan L. Koller; Weiying Yang
- International Application: PCT/IB2011/001705 WO 20110715
- International Announcement: WO2012/007836 WO 20120119
- Main IPC: C07D213/79
- IPC: C07D213/79 ; C07D213/81 ; C07D401/12 ; C07D413/12 ; C07B59/00 ; C07D413/14
Abstract:
The invention relates to substituted pyridine compounds of Formula I: (I) or a pharmaceutically acceptable salt, prodrug, or solvate thereof wherein A1, X, A2, R1a, R1b, R1c, G, and z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20130345211A1 Pyridine Compounds as Sodium Channel Blockers Public/Granted day:2013-12-26
Information query
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