Methods and system are described for cancelling interference in a microphone system. A positive bias voltage is applied to a first microphone diaphragm and a negative bias voltage is applied to a second microphone diaphragm. The diaphragms are configured to exhibit substantially the same mechanical deflection in response to acoustic pressures received by the microphone system. A differential output signal is produced by combining a positively-biased output signal from the first microphone diaphragm and a negatively-biased output signal from the second microphone diaphragm. This combining cancels common-mode interferences that are exhibited in both the positively-biased output signal and the negatively-biased output signal.