Invention Grant
US09127088B2 Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
有权
显示核激素受体活性的胰高血糖素超家族肽
- Patent Title: Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
- Patent Title (中): 显示核激素受体活性的胰高血糖素超家族肽
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Application No.: US13697018Application Date: 2011-05-10
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Publication No.: US09127088B2Publication Date: 2015-09-08
- Inventor: Richard D. DiMarchi , Bin Yang , Brian Finan
- Applicant: Richard D. DiMarchi , Bin Yang , Brian Finan
- Applicant Address: US IN Indianapolis
- Assignee: Indiana University Research and Technology Corporation
- Current Assignee: Indiana University Research and Technology Corporation
- Current Assignee Address: US IN Indianapolis
- Agency: Barnes & Thornburg LLP
- International Application: PCT/US2011/035913 WO 20110510
- International Announcement: WO2011/143209 WO 20111117
- Main IPC: A61K38/26
- IPC: A61K38/26 ; C07K14/62 ; C07K14/72 ; A61K47/48 ; C07K14/605
Abstract:
Provided herein are glucagon superfamily peptides conjugated with NHR ligands that are capable of acting at a nuclear hormone receptor. Also provided herein are pharmaceutical compositions and kits of the conjugates of the invention. Further provided herein are methods of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the conjugates of the invention.
Public/Granted literature
- US20130123178A1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY Public/Granted day:2013-05-16
Information query
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