- 专利标题： Arginine methyltransferase inhibitors and uses thereof
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申请号： US14212713申请日： 2014-03-14
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公开(公告)号： US09133189B2公开(公告)日： 2015-09-15
- 发明人: Richard Chesworth , Lorna Helen Mitchell , Gideon Shapiro , Oscar Miguel Moradei
- 申请人： Epizyme, Inc.
- 申请人地址： US MA Cambridge
- 专利权人： Epizyme, Inc.
- 当前专利权人： Epizyme, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 主分类号： A61K31/415
- IPC分类号： A61K31/415 ; A61K31/437 ; A61K31/428 ; A61K31/4155 ; A61K31/42 ; C07D231/10 ; C07D239/20 ; C07D261/06 ; C07D403/02 ; C07D277/62 ; C07D471/04 ; C07D513/02 ; C07D409/04 ; C07D403/04 ; C07D413/04 ; C07D231/12 ; C07D407/04 ; C07D411/04
摘要：
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
公开/授权文献
- US20140288105A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF 公开/授权日：2014-09-25
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