Invention Grant
US09134315B2 Use of the lactosylceramide synthase isoform B1,4GalT-V as a biomarker for cancer
有权
使用乳糖神经酰胺合酶异构体B1,4GalT-V作为癌症的生物标志物
- Patent Title: Use of the lactosylceramide synthase isoform B1,4GalT-V as a biomarker for cancer
- Patent Title (中): 使用乳糖神经酰胺合酶异构体B1,4GalT-V作为癌症的生物标志物
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Application No.: US13578657Application Date: 2010-02-12
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Publication No.: US09134315B2Publication Date: 2015-09-15
- Inventor: Subroto Chatterjee
- Applicant: Subroto Chatterjee
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Johns Hopkins Technology Transfer
- International Application: PCT/US2010/024047 WO 20100212
- International Announcement: WO2011/099980 WO 20110818
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/574 ; C12Q1/48
Abstract:
In one aspect, B1,4GalT-V, an isoform of the enzyme lactosylceramide synthase, is provided as a biomarker for cancer. Also provided are methods and compositions directed at cancers characterized by the overexpression or upregulation of the lactosylceramide synthase isoform B1,4GalT-V.
Public/Granted literature
- US20130041015A1 Use of the Lactosylceramide Synthase Isoform B1,4GALT-V as a Biomarker for Cancer Public/Granted day:2013-02-14
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