An electrode lead of a pacemaker includes at least one lead wire. The at least one lead wire includes at least one conductive core, a first insulating layer coated on an outer surface of the at least one conductive core, at least one carbon nanotube yarn spirally wound on an outer surface of the first insulating layer, and a second insulating layer coated on the surface of the at least one carbon nanotube yarn. One end of the at least one conductive core protrudes from the first insulating layer to form a naked portion. The at least one carbon nanotube yarn includes a number of carbon nanotubes joined end to end by van der Waals attractive forces. A pacemaker includes a pulse generator and the electrode lead electrically connected with the pulse generator.