Invention Grant
US09140689B2 Methods of determining susceptibility of tumors to tyrosine kinase inhibitors
有权
确定肿瘤对酪氨酸激酶抑制剂敏感性的方法
- Patent Title: Methods of determining susceptibility of tumors to tyrosine kinase inhibitors
- Patent Title (中): 确定肿瘤对酪氨酸激酶抑制剂敏感性的方法
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Application No.: US13047769Application Date: 2011-03-14
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Publication No.: US09140689B2Publication Date: 2015-09-22
- Inventor: Sara Ann Byron , Pamela Michelle Pollock
- Applicant: Sara Ann Byron , Pamela Michelle Pollock
- Applicant Address: US AZ Phoenix AU Queensland
- Assignee: Translational Genomics Research Institute,Queensland University of Technology
- Current Assignee: Translational Genomics Research Institute,Queensland University of Technology
- Current Assignee Address: US AZ Phoenix AU Queensland
- Agency: The Noblitt Group, PLLC
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/50 ; C07K14/705
Abstract:
This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly FGFR2 variants, which are linked to drug resistance. The disclosure further provides methods of diagnosis and theranosis, and development of new therapeutic agents using these molecules and fragments thereof, and kits for employing these methods and compositions.
Public/Granted literature
- US20110275084A1 METHODS OF DETERMINING SUSCEPTIBILITY OF TUMORS TO TYROSINE KINASE INHIBITORS Public/Granted day:2011-11-10
Information query
