Systems and methods are directed to configuring a portable electronic device such that a user of the portable electronic device is required to use two hands to operate the portable electronic device. In some configurations, the portable electronic device determines whether the portable electronic device is moving at a rate of speed that is greater than a predetermined threshold before requiring the user to use two hands. Alternatively, or in addition, a function, feature, and/or application of the portable electronic device may be inhibited such that two hands are required. Once the portable electronic device determines that the user is using two hands, an operation, feature, function, and/or application may then be enabled although still be inhibited.