- 专利标题： Thiochromene derivatives as HIF hydroxylase inhibitors
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申请号： US14582914申请日： 2014-12-24
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公开(公告)号： US09149476B2公开(公告)日： 2015-10-06
- 发明人: Wen-Bin Ho , Lee A. Flippin , Craig Mossman , Eric D. Turtle , Lee R. Wright
- 申请人： FibroGen, Inc.
- 申请人地址： US CA San Francisco
- 专利权人： FIBROGEN, INC.
- 当前专利权人： FIBROGEN, INC.
- 当前专利权人地址： US CA San Francisco
- 代理机构： Sheppard Mullin Richter & Hampton LLP
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K31/382 ; A61K31/4436 ; A61K31/4155 ; A61K45/06
摘要：
The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
公开/授权文献
- US20150182528A1 THIOCHROMENE DERIVATIVES AS HIF HYDROXYLASE INHIBITORS 公开/授权日：2015-07-02
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