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发明授权
US09149557B2 Process for preparing bioabsorbable sheet preparation holding thrombin 有权
制备保持凝血酶的生物可吸收片剂的方法

Process for preparing bioabsorbable sheet preparation holding thrombin
摘要：
A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.
摘要（中）：

提供了一种制备保持凝血酶的生物可吸收性片剂的方法。 一种制备保持凝血酶的生物可吸收性片剂的方法，该方法包括将由聚乙醇酸组成的生物可吸收片材浸入含有凝血酶作为活性成分的凝血酶溶液，甘油作为软化剂，吐温80作为渗透剂，以及任选的组氨酸和海藻糖 稳定剂，然后干燥以在所述生物可吸收性片材上保持凝血酶，以及通过所述方法制备保持凝血酶的生物可吸收性片剂制剂。

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