发明授权
US09150513B2 Polymorphic forms of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide
有权
4-叔丁基-N- [4-氯-2-（1-氧 - 吡啶-4-羰基） - 苯基] - 苯磺酰胺的钠盐的多晶型形式
![Polymorphic forms of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide](/docs/US/2015-10-06/US09150513B2/abs.jpg.600x600.jpg)
- 专利标题： Polymorphic forms of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide
- 专利标题（中）： 4-叔丁基-N- [4-氯-2-（1-氧 - 吡啶-4-羰基） - 苯基] - 苯磺酰胺的钠盐的多晶型形式
-
申请号： US14234279申请日： 2012-07-20
-
公开(公告)号： US09150513B2公开(公告)日： 2015-10-06
- 发明人: Joanna Bis , David H. Igo
- 申请人： Joanna Bis , David H. Igo
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 代理机构： Brinks Gilson & Lione
- 代理商 Ryan L. Marshall
- 国际申请： PCT/US2012/047513 WO 20120720
- 国际公布： WO2013/016156 WO 20130131
- 主分类号： C07D211/70
- IPC分类号： C07D211/70 ; C07D213/89 ; A61K31/44
![Polymorphic forms of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide](/abs-image/US/2015/10/06/US09150513B2/abs.jpg.150x150.jpg)
摘要：
Disclosed are novel polymorphic solvated and desolvated forms of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)phenyl]-benzenesulfonamide. One embodiment of the present invention is directed to a crystalline sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]benzenesulfonamide (hereinafter “Compound A-1,4-dioxane/water solvate”), wherein the crystalline form is characterized by an X-ray powder diffraction pattern comprising diffraction angles (° 28), when measured using Cu Ku radiation, at about 4.0, 8.1, 10.1, 14.2, 16.2, 18.6, 20.3, 24.7, 25.0, and 26.5.
公开/授权文献
信息查询
