Invention Grant
US09150582B2 Composition and method for neuropeptide S receptor (NPSR) antagonists
有权
神经肽S受体（NPSR）拮抗剂的组合物和方法
- Patent Title: Composition and method for neuropeptide S receptor (NPSR) antagonists
- Patent Title (中): 神经肽S受体（NPSR）拮抗剂的组合物和方法
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Application No.: US14363079Application Date: 2012-12-06
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Publication No.: US09150582B2Publication Date: 2015-10-06
- Inventor: Scott Runyon , Yanan Zhang , Carla Hassler , Brian Gilmour
- Applicant: RESEARCH TRIANGLE INSTITUTE
- Applicant Address: US NC Research Triangle Park
- Assignee: RESEARCH TRIANGLE INSTITUTE
- Current Assignee: RESEARCH TRIANGLE INSTITUTE
- Current Assignee Address: US NC Research Triangle Park
- Agency: Hultquist, PLLC
- Agent Mary B. Grant
- International Application: PCT/US2012/068257 WO 20121206
- International Announcement: WO2013/086200 WO 20130613
- Main IPC: C07D491/04
- IPC: C07D491/04 ; A61K31/4355 ; C07D491/048 ; C07D491/10 ; C07D491/107
Abstract:
Neuropeptide S receptor antagonists are provided that bind in functional assays to neuropeptide S receptors; methods are provided for use of these antagonists in treatment of conditions or disease states that are ameliorated by blocking of the neuropeptide S receptor, including substance abuse and substance abuse relapse; and for use of neuropeptide S receptor antagonists in the manufacture of therapeutics and pro-drugs for therapeutics useful in disease states and conditions sensitive to binding of the neuropeptide S receptor.
Public/Granted literature
- US20150057268A1 COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS Public/Granted day:2015-02-26
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