发明授权
US09157072B2 Hybrid baculovirus having the capability of infecting at least three insect hosts and uses thereof
有权
具有感染至少三种昆虫宿主的能力的杂种杆状病毒及其用途
- 专利标题： Hybrid baculovirus having the capability of infecting at least three insect hosts and uses thereof
- 专利标题（中）： 具有感染至少三种昆虫宿主的能力的杂种杆状病毒及其用途
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申请号： US14277892申请日： 2014-05-15
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公开(公告)号： US09157072B2公开(公告)日： 2015-10-13
- 发明人: Tzong-Yuan Wu , Mean-Shine Chen , Chao-Yi Teng , Ying-Ju Chen
- 申请人： Chung Yuan Christian University
- 申请人地址： TW Jhongli, Taoyuan County
- 专利权人： CHUNG YUAN CHRISTIAN UNIVERSITY
- 当前专利权人： CHUNG YUAN CHRISTIAN UNIVERSITY
- 当前专利权人地址： TW Jhongli, Taoyuan County
- 代理机构： Muncy, Geissler, Olds & Lowe, P.C.
- 主分类号： C12N7/00
- IPC分类号： C12N7/00
摘要：
Disclosed herein is an Autographa californica multiple nucleopolyhedrovirus (AcMNPV) based hybrid baculovirus and its uses thereof. The AcMNPV based hybrid baculovirus is capable of infecting different hosts, and comprises Bombyx mori nuclear polyhedrosis virus (BmNPV) genes of lef9, vlf1, p6.9, and vp80; Maruca vitrata multiple nucleopolyhedrovirus (MaviMNPV) genes of lef2, orf1629, and pe38; and AcMNPV/BmNPV/MaviMNPV-hybrid genes of pk1, lef8, DNA pol, GP41, helicase, orf94, VP1054, orf65, lef4, lef5, and orf99. The AcMNPV based hybrid baculovirus is therefore useful as a bio-tool or bio-insecticide for its capability of delivering genes for production or expression of toxic proteins in at least three different insect hosts.
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