发明授权
- 专利标题: Sustained release intraocular implants and methods for treating ocular vasculopathies
- 专利标题(中): 持续释放眼内植入物和治疗眼血管病变的方法
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申请号: US12024010申请日: 2008-01-31
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公开(公告)号: US09161938B2公开(公告)日: 2015-10-20
- 发明人: Glenn T. Huang , Brittany Jackson , James A. Burke , Ton Lin , Patrick M. Hughes , Larry A. Wheeler , Rosy Sheng Donn
- 申请人: Glenn T. Huang , Brittany Jackson , James A. Burke , Ton Lin , Patrick M. Hughes , Larry A. Wheeler , Rosy Sheng Donn
- 申请人地址: US CA Irvine
- 专利权人: Allergan, Inc.
- 当前专利权人: Allergan, Inc.
- 当前专利权人地址: US CA Irvine
- 代理商 Laura L. Wine; Joel B. German; Debra D. Condino
- 主分类号: A61K31/498
- IPC分类号: A61K31/498 ; A61K9/14 ; A61L31/14 ; C08L67/04 ; A61K9/20 ; A61L31/16 ; A61L27/58 ; A61K9/00
摘要:
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, among others.