发明授权
US09163241B2 Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
有权
用于HIV-1治疗的细胞型特异性适体 - siRNA递送系统
- 专利标题: Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
- 专利标题(中): 用于HIV-1治疗的细胞型特异性适体 - siRNA递送系统
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申请号: US13230088申请日: 2011-09-12
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公开(公告)号: US09163241B2公开(公告)日: 2015-10-20
- 发明人: John J. Rossi , Jiehua Zhou
- 申请人: John J. Rossi , Jiehua Zhou
- 申请人地址: US CA Duarte
- 专利权人: CITY OF HOPE
- 当前专利权人: CITY OF HOPE
- 当前专利权人地址: US CA Duarte
- 代理机构: Rothwell, Figg, Ernst & Manbeck P.C.
- 主分类号: C12N15/11
- IPC分类号: C12N15/11 ; C12N15/115 ; C12N15/113
摘要:
The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer.
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