The present disclosure provides a crosstalk compensation method and a display apparatus using the same. The method includes: configuring a compensation range with the compensation range set between the maximum gray level and the minimum gray level; establishing a look-up table to record compensation values for each gray level in the compensation range; determining whether the gray level of a first color sub-pixel on the display panel is set within the compensating range. When it is determined that the gray level of the first color sub-pixel is set within the compensation range selects a compensating value for configuring an initial gray level of an adjacent second color sub-pixel to a correction gray level. When it is determined that the gray level of the first color sub-pixel is set outside the compensation range, maintains the gray level of the second color sub-pixel at the initial gray level.