In a method of driving an organic light emitting display device, a first data signal constituting an image frame is sequentially written into first pixel circuits coupled to first scan-lines by sequentially performing a scanning operation on the first scan-lines in a first direction, a second data signal constituting the image frame is sequentially written into second pixel circuits coupled to second scan-lines by sequentially performing the scanning operation on the second scan-lines in a second direction, and the image frame is displayed by controlling the first and second pixel circuits to simultaneously emit light.