Invention Grant
US09168254B2 Polymorphs of ARRY-380, a selective HER 2 inhibitor and pharmaceutical compositions containing them
有权
ARRY-380，选择性HER2抑制剂和含有它们的药物组合物的多晶型物
- Patent Title: Polymorphs of ARRY-380, a selective HER 2 inhibitor and pharmaceutical compositions containing them
- Patent Title (中): ARRY-380，选择性HER2抑制剂和含有它们的药物组合物的多晶型物
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Application No.: US14351835Application Date: 2012-10-12
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Publication No.: US09168254B2Publication Date: 2015-10-27
- Inventor: Donald T. Corson , Christopher M. Lindemann , Daniel J. Watson
- Applicant: Array BioPharma Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Agent Cory M. Williams
- International Application: PCT/US2012/060138 WO 20121012
- International Announcement: WO2013/056183 WO 20130418
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437 ; A61K31/517 ; A61K45/06
Abstract:
Polymorphs of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine are provided herein. Processes for preparing the polymorphs and pharmaceutical composition comprising the polymorphs are also disclosed.
Public/Granted literature
- US20140243361A1 POLYMORPHS OF ARRY-380, A SELECTIVE HERB2 INHIBITOR AND PHARMACEUTICAL COMPOSITIONS CONTIANING THEM Public/Granted day:2014-08-28
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