A one-handed activation device includes a hand attachment assembly having an activatable device attachment portion securable to at least a portion of a user's hand and a first switch portion securable to at least a portion of one of a proximal phalanx of a user's thumb and a middle phalanx of a user's finger. The one-handed activation device further includes an activatable device configured to be selectively activated that is secured to the activatable device attachment portion and a first switch configured to selectively activate the activatable device. The first switch is secured to the first switch portion and it is positioned such that the first switch substantially overlies an extensor surface of one of the proximal phalanx of the user's thumb and the middle phalanx of the user's finger.